setup.exe is a program which is probably NOT a virus or malware. So, if setup.exe is on your computer, it is probably ok, and will NOT be a cause for concern. Even if your system is clean, it is still recommended to run a well-known antivirus with a good track record, in order to defend yourself against viruses and malware.
Normally, this application is located in C:\2fefb8b402d21515db98dcb752f19f84\Setup.exe.
The MD5 fingerprint for this executable is f234430eb91bf40de283fe40eafdebc9.
This application does NOT run as a Windows service. This is normally a good sign.
This application runs in 32-bit mode. It does not benefit of the full set of features of current computer CPUs. This ordinarily happens because the publishers did not bother to upgrade it to 64-bit code.
The description extracted from the exe is Setup Installer.
File version 12.0.51720.34280 built by: FX452RTMGDR.
Company Microsoft Corporation.
Legal copyright © Microsoft Corporation. All rights reserved..
This program does NOT have visible elements of user interface. This is usually a bad thing.
setup.exe has a digital signature. Nowadays most serious software applications are digitally signed.
The digital signature attached to setup.exe checks out perfectly. This is most likely a clean, ok program.
Digitally signed by: Microsoft Corporation
Certificate's issuer name: Microsoft Code Signing PCA
This program does NOT have an uninstall routine stored in registry.